Lab pipettes – Buying guide & Comparison
If you are short on time, and you just want to find the best pipettes, this concise paragraph should help you get just the model you need. According to our research, the Glove Scientific 139050 LDPE 100 Pack is worth considering as it can help you with performing multiple tasks both in the lab and at home. Every pipette comes with a capacity of 23 milliliters and has a length of 300mm. What this means is that you won’t have to make an effort to grab the liquid as the size of the product will enable you to do just that without having to come into contact with the substance. Moreover, these pipettes are made of low-density polyethylene, which renders them non-slippery and capable of being frozen in liquid nitrogen. In case the Glove Scientific 139050 LDPE 100 Pack is no longer available, we suggest opting for the next best choice, the SEOH 41121513 Glass Droppers.
What is the best brand of pipettes? Which ones fit the application you have in mind? If you’re having a bit of trouble providing an answer for these two questions but plan to get some of the best laboratory pipettes available for sale out there, we’re here to help you. In order to save you some time that you’d have to spend reading countless articles about selecting the right products, we suggest you check out our simple buying guide. It can assist you when it comes to making an informed decision.
This is one of the first factors you ought to keep an eye on. Just how much liquid can you transfer with the help of the pipette you might want to purchase? Bear in mind that sometimes, bigger is better, and we’re not here to disagree. If you have no idea whether you might require adding more and more liquid to your sample, perhaps you’d benefit from using a sizeable pipette. If, on the other hand, your working protocol requires you to add just one milliliter of liquid per sample, you already know the volume you’re looking for.
Not all of these products are designed the same, and the same rule applies in the case of the applications they might be a great fit for. If the area you work in needs somewhat accurate measurements, what you may be in need of is a graduated pipette. If you can use just your eyes to tell how much liquid you’ve poured into a Petri dish, for example, then you may not need the services offered by a graduated model. There aren’t any significant differences in regard to the price of graduated and non-graduated items, so you needn’t worry about spending too much money on one or the other.
For some, the best ergonomic pipettes are made of glass, whereas others simply prefer the convenience offered by plastic alternatives. Glass has some net advantages over plastic, which are mostly related to the fact that the items constructed of this material can typically be reused. Most glass pipettes can be washed and even sterilized, depending on the durability of the parts in the product. From what we have gathered on the topic, glass models are usually a little more expensive compared to their plastic counterparts, but it really boils down to whether you’re comfortable with using a rubber bulb or one that’s integrated into the body of the item and has been made of a rather flexible type of plastic. The vast majority of these last options cannot be sterilized using a substance or heat, which is why they are traditionally made to be disposed of right after having been used.
Price, recommendations, and manufacturing brands
In most cases, you are likely to see that even the best manual pipettes don’t cost a lot of money. Depending on their capacity, packs of 100 pieces can be found for as little as five dollars or even less. The cost does add up when you’re working in a busy lab where hundreds of samples are processed on a daily basis. That’s why it might pay off to continue your research and go through the best pipette reviews as there are many professionals who might report an issue if they’ve come across any. As for the brand that has manufactured the pipette, we recommend buying a model made by companies that are renowned for the quality of their products. Karter Scientific and SEOH are just two examples.
15 Best Lab Pipettes (Reviews) in 2021
The best pipettes are showcased below. We’ve taken the time to check the ratings acquired by these models, and we’ve eventually settled on a short selection of the most remarkable ones. All of the following suggestions are praised for being convenient, easy to use, and entirely capable of doing their job.
- 1. Globe Scientific 139050 LDPE Extra Long Transfer Pipet
- 2. Seoh 4 inch Glass Pipette Droppers
- 3. Karter Scientific 206H2 3ml Grad Transfer Pipettes
- 4. Seoh Plastic Transfer Pipettes 1ml Graduated
- 5. Samco Scientific 282 Polyethylene 0.3mL Graduated Pediatric Pipette
- 6. A&D Weighing MPA Pipette 100 to 1200 μL
- 7. BrandTech 2705355 Electronic Pipettor
- 8. Eppendorf Xplorer electronic pipette 4861000171
- 9. VistaLab Ovation 12-Channel Adjustable Electronic Pipettor
- 10. VistaLab Ovation Single-Channel Adjustable Electronic Pipettor
1. Globe Scientific 139050 LDPE Extra Long Transfer Pipet
Having been made from low-density polyethylene, these pipettes are easy to use, convenient, and above all, versatile. Their length and capacity render them capable of being just the right instrument for performing a broad array of tasks both at the lab and at home.
The pack contains a number of 100 items, so you’ll be getting your money’s worth. Despite being somewhat affordable particularly when compared to other choices available for purchase these days, this alternative consists of a kit of non-sterile user-friendly pipets that you can utilize for transferring biological fluids, as well as acids.
Something worth noting about this choice is that it can be frozen in liquid nitrogen, which is an aspect that cannot be said about many other products in this line. The polyethylene renders the pipets non-slippery, so you will be able to grab them even when using gloves, and you won’t have to worry about dropping them by accident.
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2. Seoh 4 inch Glass Pipette Droppers
As we were mentioning in the buying guide, sometimes it pays off to use glass pipettes instead of plastic one. When handling sensitive liquids that may or may not be affected by the compounds released by plastic if the transfer substance is hot, it’s safe to say that the services offered by a glass product can be much appreciated.
As is the case with many other options constructed of the same material, these pipettes come with bulbs made of rubber.
While it is difficult to estimate the capacity of these droppers as there is no information available regarding the volume, the items measure 4 inches, and once the bulb has been removed, the glass part is about 3.5 inches long.
In spite of the fact that the pack comes with just 12 items, it’s safe to say that this option is worth considering mainly because it can be reused.
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3. Karter Scientific 206H2 3ml Grad Transfer Pipettes
Karter Scientific is one of the most well-known brands in the industry of manufacturing high-quality lab equipment, including pipettes and pipettors.
That’s why it was to be expected that this pack is one of the top recommended ones we’ve come across. First of all, the volume of these pipettes is significantly higher when compared to the items we’ve showcased prior to the 206H2. As such, every item in the pack containing 500 can be used to transfer up to 7 ml.
What’s more, the graduations that you will find conveniently placed on the sides of the pipettes make it possible for you to measure the liquid in intervals of 0.5 ml.
Because they have been constructed out of low-density polyethylene, these items should be disposed of right after use as they are non sterile and cannot be utilized time and time again. Owners recommend them for measuring medicine for pets and other home applications, as well.
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4. Seoh Plastic Transfer Pipettes 1ml Graduated
As is the case with the previously mentioned suggestion, this one is also manufactured by Karter Scientific, a US-based manufacturer with an excellent reputation. If you’re in need of many pipettes, maybe you ought to give a chance to this pack as it contains five hundred items.
Every one of the pieces that can be found in the box can be utilized for transferring up to 1 ml of liquid and the 0.25 ml graduation intervals may come in handy, at some point or the other.
Due to the excellent construction and functionality of this model, it doesn’t come as a surprise that its quality has been praised by many satisfied owners.
We’ve noticed that over one hundred individuals took the time to write detailed favorable reviews about the performance and build of these pipettes. While some employ them for chemistry, others transfer oils or liquor with their help.
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5. Samco Scientific 282 Polyethylene 0.3mL Graduated Pediatric Pipette
Just like with one of the models we’ve showcased earlier on, the 206H3 can be used for transferring up to seven milliliters of liquid.
The main difference between the unit we’ve described above and this one consists of the fact that this pack is composed of just one hundred pipettes, which means that it addresses users who don’t require that many items. Also, it is important to note that the bulb draw of these pipettes is 3.2 ml.
Having been constructed out of low-density polyethylene, these pipettes can be utilized with a wide array of substances ranging from acids and biological fluids of which the temperature can be anywhere in the span of -50 degrees Celsius and 90 degrees Celsius.
In order to preserve samples, the company recommends sealing the pipettes with the help of heat or the use of liquid nitrogen. Over time, the 206H3 pack has garnered over 200 positive Amazon reviews.
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Top electronic pipettor reviews in 2021
If you’ve been trying to purchase one of the best electronic pipettes available for sale out there but find it hard to sift through the many models that can be discovered in today’s market, you’re in the right place. Since reading a bit more information about the product you ought to spend your money on and on how to choose it wisely never hurt anyone, we’ve created a simple buying guide that can hopefully assist you in making the right decision. Just make sure that you always consider your needs before anything else as this consideration can be key to becoming a happy user.
Only you are aware of the application you will be using the pipettor for. That’s why you need to decide the capacity you might benefit from utilizing. In some respects, bigger is better as this way, you’ll be able to process either fewer samples or more, depending on the occasion that arises. If the lab you work in processes many samples every day, you may have to look for a pipettor with a higher capacity. Typically, we’ve noticed that most of these high-capacity alternatives can cost a pretty penny, so be prepared to make an investment if that’s what you are looking for.
Depending on the field you work in, you may need to calibrate the pipettor every six months or every three months. For example, most of the brands that are manufacturing drugs or food items have to calibrate their pipettes and micropipettes on a quarterly basis. Labs in schools may need to do the same thing only on a yearly basis because there is no danger to humans whatsoever when the substances are not utilized in products that may end up consumed by customers.
Students and professionals in areas such as forensics and research have to calibrate their pipettors every month because otherwise, the quality of the results may suffer from the lack of accuracy of the device. Official calibration is a subject that needs looking into, but self-calibration is one of the features that might come in handy for lab professionals who work with a lot of samples every day. This makes it possible for them to be absolutely sure that the amount of substance that they will drop using the electronic pipette will be correct every time.
Single-channel or multi-channel
This is yet another factor that you have to give some thought to because it is strictly related to the area you work in and the application you may have to perform with the help of the device. Some multi-channel models can distribute substances into up to twelve containers at the same time and that is due to the fact that their design allows them to do exactly this. On the other hand, single-channel alternatives are good choices for less busy labs or for professionals on a budget, who simply work with fewer samples.
Ease of use
In the end, it all boils down to how convenient and easy to use the device you’re opting for really is. Some automatic alternatives are more user-friendly than others, particularly if they are equipped with features that allow them to prevent repetitive stress injuries. Do you have to press a button each time you need to place an amount of liquid into the sample or is the device smart enough to do so on its own? On a side note, it wouldn’t hurt if you looked for the best electronic pipettor reviews to see what other users had to say about the product you’re considering.
The best electronic pipettors are showcased below. We have taken the time to look at the features and advantages offered by these suggestions and we have come up with a limited selection composed of the models that are both cost-efficient and capable of excellent performance.
6. A&D Weighing MPA Pipette 100 to 1200 μL
If getting a high-quality single-channel electronic pipettor is what you’re trying to do, perhaps it is high time you checked out the MPA-1200.
It seems to have all the features that might be required in order to improve your workflow and increase the accuracy of your processed samples. On the one hand, considering this unit is advantageous because it comes with its own charger.
On the other hand, the model has a multiple dispensing mode which significantly adds to the repeatability and efficiency you are likely to benefit from. Besides, it should be noted that the MPA-1200 has a self-calibration function that can correct errors regarding the handling, liquid temperature, and the tip variations.
What’s more, this model offers the convenience of four individual operation modes, nine program memories, as well as eighteen hundred pipette cycles. The accuracy of this unit is ±5% and the capacity ranges from 100 to 1,200 microliters.
Offering a generous capacity range between 100 to 1,200 microliters, this electronic pipette simplifies the transfer of samples from one vessel to another or to a slide minus the inconsistencies when using a manual pipette.
Very small amounts of liquid can be easily taken from one receptacle to another with ease as this makes a cost-efficient alternative to mechanical pipette models. You can take samples with less effort and more accuracy to the last drop.
Expect efficiency and repeatability of pipetting operations thanks to the Electronic Dispensing Mode of this electronic pipette.
With its self-calibration feature, this tool ensures accuracy in the laboratory setting especially when working with samples that are difficult to obtain or prepare.
Using this instead of a mechanical pipette lessens the incidence of repetitive thumb injury since you only use light and short key strokes with the ball of your index finger to obtain samples.
The tool may be a challenge to clean when it gets contaminated with sample beyond the pipette tip.
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7. BrandTech 2705355 Electronic Pipettor
Some prospective buyers may have to consider finer and more delicate alternatives compared to the one we’ve showcased earlier on.
This is the exact case with the BrandTech Transferpette 705340 as it can be used for volumes ranging from 2 microliters to 20 microliters.
While the model doesn’t come with the same user-friendly features belonging to the previously discussed A&D Weighing alternative, it has been granted an independent Ergonomic Approved certification and as such, it may be reasonably easy to use. Additionally, you’re probably going to enjoy using the large LCD screen as it can display all of the settings being used and being modified by the user.
As is the case with other products in the same line, the BrandTech Transferpette 705340 comes with a rechargeable battery which is more than capable of offering up to 4,000 pipetting cycles for every charge. The charging stand needs to be bought separately.
Equipped with a maximum volume of 0.02 milliliters and a minimum volume of 2 microliters, this device is useful for working with minimal quantities of sample in the lab setting.
Providing an accuracy of ±0.2 UL or ±1.0 percent, this implement ensures accuracy in every drop of sample processed in the lab while facilitating repeatability.
This single-channel electronic pipette is geared with a soft-touch pipetting key along with an adjustable finger rest, contoured handle, and a well-designed tip cone, which all work together to minimize the operational forces required for effective use.
Having earned approval for being ergonomic to use, this model has been subjected to the acknowledged TUV testing service and an OSHA-accredited independent testing lab to certify it performs as designed.
The large LCD screen lets you view all the settings clearly. Every function comes with a dedicated control to minimize errors due to unwanted changes in volume or the accidental ejection from the tip.
Those with short fingers or small hands may have difficulty operating the device using just a single hand.
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8. Eppendorf Xplorer electronic pipette 4861000171
Electronic pipettes by Eppendorf can sometimes take a toll on a prospective buyer’s budget, but one thing’s for sure – multi-channel options don’t get better than this.
After all, Eppendorf is one of the most reputable brands in the industry of manufacturing lab equipment including pipettes and pipettors, which is why it is only natural that this product is in complete accordance with the company’s quality standards.
Having been designed for professional standards, the model offers optimal support as well as an intuitive concept which is based on the traditional features of most pipettors constructed by Eppendorf. You’ll find that this multi-channel model has precise adjustable parameters, user-friendly characteristics, and manages to offer complete control over the entire process.
The 4861000171 is a 12-channel pipettor with a capacity ranging from 50 to 1,200 microliters and an accuracy of ±6% at 120 microliters. Even though it might be less reasonably priced than other options out there, the 4861000171 is undoubtedly worth considering.
This model is a multi-channel pipette that simplifies the taking of multiple quantities of samples, which can be very useful for quantitative essays where you need not just one but a number of amounts for study.
Designed to adhere to professional standards, this model delivers dependable support along with an intuitive mechanism of sample transfer compared to mechanical pipettes.
The sample quantity parameters can be adjusted with ease and with push-button simplicity so you control everything from the sample preparation and taking to the transfer.
You will appreciate that this 12-channel pipettor features a capacity ranging from 50 to 1,200 microliters plus an accuracy of ±6% at 120 microliters.
Users will appreciate that this unit is solidly built for lasting durability to support the needs of the modern laboratory.
The large pipette head appears to be quite imposing and might take plenty of practice to learn how to optimize.
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9. VistaLab Ovation 12-Channel Adjustable Electronic Pipettor
VistaLab is another well-known manufacturer of excellent pipettors, and most of the products designed by the company are ergonomically correct and easy to use.
In fact, this one has been manufactured uniquely, in that it can minimize the tension and exertion, as well as the contact pressure required on the part of the user. Handling the item is efficient and less time-consuming compared to employing other multi-channel pipettors.
While the volume range of this model is significantly lower compared to the Eppendorf multi-channel pipette as the VistaLab one is only capable of handling between 25 and 850 microliters, it is also true that this product is more affordable than the Eppendorf alternative.
Besides, both the tip ejector and the universal AC power adapter are part of the deal, and they also increase the value of the device. Prospective buyers are advised that this product is intended for right-handed individuals. In case left-handed ones also want to buy the model, they have to get in touch with customer support first.
You can tell this electronic pipettor is designed to revolutionize the concept of liquid transfer. It reduces the fatigue, pain, and stress from repeated and day-long pipetting. There will be no tensions on your elbows and shoulders even if you transfer microscopic amounts of liquid for hours.
Geared to keep your hand in the neutral position at all times, this is an ergonomically designed micropipette with a low-pressure, form-fitting plunger to manually control the speed of aspiration and dispensing while requiring minimal effort.
Suitable for use with fragile membranes that are easily disturbed or liquids that get air bubbles with the slightest disruption, this electronic pipette provides fast and easy handling.
The revolutionary tip acquisition system emits an audible ‘click’ to assure you that all tips have been fitted tightly.
All the tips can be ejected simultaneously and easily with a simple touch of a button, preventing contamination by contact. The large LCD display and motor-operated adjustments ensure precise liquid transfers.
Just like any technologically advanced device, this one might require practice to ensure an optimal functionality.
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10. VistaLab Ovation Single-Channel Adjustable Electronic Pipettor
The 1065-1250 is yet another interesting suggestion particularly if you have been trying to get a fully functional single-channel electronic pipettor that’s worth its weight in gold.
This product can handle liquid volumes ranging from 25 to 1,250 microliters. The accuracy of the device is ±0.8% at 625 microliters, which is more than decent based on the information that we have gathered about the correct sample processing needs of most professionals.
As is the case with the multi-channel variant we detailed the features of earlier on, this one has been designed with the user in mind, because it manages to reduce the causes of fatigue and pain, as well as the stress caused by constant pipetting. In addition, the model has a large LCD display that allows owners to check on the data they may need to see in order to be reassured that the process is going as it should.
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Top lab pipettor reviews in 2021
Manual and electronic pipettors have been around for quite some time. Due to the rise in numbers of the products that can be found on the market, prospective buyers can feel a bit baffled as to which one really is the best. Research takes time, and we’re well-aware of that, which is why we have compiled all of the crucial information we have come across in a short yet comprehensive buying guide. If you keep on reading, you’ll find all the factors you need to take into account to make sure that you choose wisely.
The volume range is one of the first details you’ll have to look at, mainly because it needs to be correlated with the application you have in mind. There are few cases where laboratories actually own just one pipettor, so it might be a good idea to see whether you prefer getting one with a generous volume range or it pays off to purchase different kinds of pipettors, each with its own capacity. Some of the standard sizes we’ve come across range from 2 to 20 microliters, 20 to 200 microliters, and even 200 to 1000 microliters. It goes without saying that your requirements have to come first, in this case, even more so if you will be the one utilizing the pipettor. It is important to note that, the wider the limits of the volume range, the less likely it is for the unit to be extremely precise. That’s why many brands manufacture sizes particularly intended for performing accurate measurements.
Manual or electronic
Whether you’re looking for multichannel pipettors or plan to stick to one of the many single channel pipettors out there, the fact of the matter is that you will have to decide if you want a manual or an electronic product. There are both advantages and disadvantages to choosing one of these two types, and the costs are significantly different from one another. For instance, electronic models are considerably more expensive compared to their manual counterparts, but they provide the undeniable advantage of an input pad, which is why they might be more precise, in the end. These electronic options are highly recommended for professionals who spend their time pipetting all day long.
By contrast, the volume of manual pipettors has to be adjusted using a knob and since the interference of an operator is significant, in this case, using these models might leave room for human errors. It goes without saying that both electronic and manual options can feature either a digital or a non-digital display. As a side note, manual units are single-channel pipettors, which makes them a good choice for educational settings, as well as small-scale labs where professionals don’t work with a very high number of samples on a daily basis.
Ease of use and convenience
Operating a pipettor should never be an insurmountable feat. If you intend to purchase the item online, there’s only one way of telling whether or not the product is easy to use, and it’s by reading the best pipettor reviews. Naturally, there are devices which haven’t yet gathered many reviews, but if you really are keen on buying them, you’ll inevitably read some about them.
For example, a display set on the side of the unit is handy because you’ll be able to keep an eye on the volume of the liquid all of the time. Another feature you ought to give some thought to is an ergonomic design. By the same token, there are models which have been developed to reduce the thumb strain that’s likely to be caused by utilizing a pipettor time and time again.
The best pipettors are showcased below. We’ve taken a chance to check what owners had to say about these products. Since these models have garnered some of the most remarkable ratings on Amazon and other online retailers, we felt compelled to recommend them by adding them to our selection. Rest assured, in spite of their user-friendly features, none of these products have off-putting prices.
11. Scilogex 71311101 MicroPette Plus
Scilogex is one of the trusted brands in the industry of manufacturing excellent pipettors, which is why it goes without saying that this model does exactly what it has been designed to do.
Priced at just under seventy dollars, this pipettor makes it possible for owners to utilize it with volumes ranging from 0.1 to 2.5 microliters, depending on the use they might have in mind.
Although this is a single-channel micropipette that comes with a manual volume control, the fact that it is both easy to use and convenient makes it a good choice for people who’d like to avoid the high costs of getting an electronic option.
The model comes equipped with a digit counter located on the side, which means that lab professionals will be able to glance at the volume selection without rotating the device. Based on the owner feedback we’ve stumbled upon regarding the services offered by the 71311101, it looks as if it offers accurate and consistent results.
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12. Scilogex 71211101
Much like the product we’ve described earlier on, this one can be purchased in a wide array of volume ranges. The 0.1 to 2.5 microliter model also features a digit counter conveniently constructed on the side of the unit of which the role is to indicate the volume that has been selected by the user.
There is a difference between the unit we’ve talked about above and the 71211101 and it consists of the fact that only the nose of the product can be sterilized using an autoclave.
This might be less beneficial under certain circumstances, particularly if you believe that avoiding to sterilize the entire device can tamper with the accuracy of your samples.
The people who’ve bought the 71211101 seem to have nothing but good things to say about it, especially as it offers a smooth thumb pump action and is comfortable to hold in one’s hand.
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13. Thermo Scientific 4642100 Finnpipette F2
Another company that has lab professionals looking into their products is Thermo Scientific, mostly because it has been designing high-quality equipment intended for laboratory use for quite a while now.
The 4642100 Finpipette F2 has a volume ranging from 0.5 to 5 microliters, which means that its capacity is far higher compared to the options we’ve described earlier on. In other words, you’ll have to look at your requirements, once more, and decide whether this capacity is the right one for you.
Even though it is also a single-channel manual micropipette, the product features a unique locking mechanism that makes it possible for volume changes to avoid happening accidentally.
Without a doubt, this is an advantage that cannot be denied as accidents tend to occur when using manual devices. This micropipette can be sterilized in its entirety, so it is highly recommended for processing sterile samples.
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14. Globe Scientific Diamond Advance 3342-1000
This Globe Scientific model is undoubtedly different compared to the models mentioned above, and that’s because it has a fixed volume. In other words, you won’t be able to adjust the capacity of the device depending on the application you may want to utilize it for.
Instead, you’ll have to make do with the 1000 microliters that you can transport and drop with the help of this model. However, the Diamond Advance 3342-1000 does provide a series of advantages, because it is ergonomic, easy to clean, and fully autoclavable.
In addition, the product has been equipped with a sizeable 4-digit display window. Thanks to the way it has been constructed, the Globe Scientific Diamond Advance 3342-1000 seems to be a great fit both for left-handed and right-handed users.
Finally, the unit is backed by a 3-year warranty, and it’s undoubtedly reassuring to know that it has been built in an ISO 17025 accredited lab.
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15. ACTGene Agile ACT-AMSP-10
If your budget doesn’t allow you to spend more than one hundred fifty dollars on a single-channel manual pipettor, but you do intend to get more than enough value for the price, maybe it’s high time you checked out the ACTGene Agile ACT-AMSP-10.
In spite of the fact that it is among the most affordable choices we’ve discovered while sifting through the ones available on the market today, the ACT-AMSP-10 definitely raises up to par.
The volume of this particular unit ranges from 1 to 10 microliters, and as is the case with the rest of the products we’ve suggested earlier on, this one features a digit counter.
In some respects, the ACT-AMSP-10 has high-end features such as the ones donned by the previously mentioned Thermo Scientific model, especially as it features a locking mechanism, as well as a finger rest. The product can also be purchased in different volumes, such as 2 to 20, 20 to 200, and 100 to 1000 microliters.
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DMtse Plastic Transfer Pipettes
The DMtse pack is composed of one hundred items with a capacity of 3 milliliters each. All of the products have been manufactured out of plastic, and it should be underlined that they cannot be reused as they are non sterile and can’t be cleaned using any method currently being used in laboratories all over the world.
The neat thing about this suggestion is that it consists of graduated pipettes, and although the entire volume is 3 ml, one can make use of the graduations so that he or she releases 0.5 ml or more.
The owner feedback regarding the services offered by the DMtse pack is mostly favorable, as we have noticed that many buyers use them for purposes other than lab applications, as well. For instance, there have been people who reported that they used them successfully for adding shots to their cupcakes, whereas others employ the pipettes for transferring essential oils to vials.